Wednesday, November 7, 2018

PATM Research Paper 2018

Click on icon to see paper (English translation)
Original in Japanese

PATM Research Paper

Click on icon to see
Power Point Presentation
Yoshika Sekine, PhD, Professor at Tokai University, Japan, President, Society of Indoor Environment, Japan, along with a team of scientists carried out research on PATM Syndrome . We are highly thankful to all of them for giving their precious time to researching and exploring PATM Syndrome.

On April 14, 2018, the Founder and Executive Director of MEBO Research, Maria de la Torre, asked Prof. Sekine to help present his work to raise awareness throughout the globe from the MEBO Annual Conference & Meetup held in Savannah, Georgia this year.Our most sincere thanks to Prof. Yoshika for creating a PowerPoint presentation and providing us with his research paper on the study . We have shared this in many forums through platform of MEBO . The research paper was in Japanese language so MEBO arranged to translate the PATM Syndrome research paper in English language with the help of Director of Community Outreach and Strategy , Mehmet Ali.

Again Sir, thanks you very much for working on this syndrome. Please do not hesitate to contact me if you believe there is anything I can do to support your work.

Research paper is property of Prof. Yoshika and their co-authors and is translated and presented in the MEBO sites with their expressed consent.  We want to raise awareness throughout the globe about PATM syndrome using this effort of Prof and his team of scientists. I hope this information is helpful to other scientists and inspires future research into PATM...



Friday, June 15, 2018

To qualify as participant MEBO/uBiome Study


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The Principal Investigator of the uBiome grant-funded MEBO research study, "Dynamics of the Gut Microbiota in Idiopathic Malodor Production", Irene Gabashvili, PhD., MEBO Scientific Director, has written a post about the study in her company's blog, AURAMETRIX. This post includes MEBO/PATM Life Quality Test, "MEBO means metabolic body odor and it includes systemic body odor, bad breath and episodes of malodor NOT related to hygiene or flatulence. PATM denotes "People Allergic To Me" condition. The survey asks about symptoms In the past 24 hours or past few days, up to a week before taking this test."

We are starting pre-screening our candidates to find qualified participants, based on prior test results and ability to accurately report information.

Participants will be asked to submit their samples to uBiome on as different days in terms of their well-being/mood/symptoms as possible. MEBO is a condition of ups and downs. One day you may be completely odor-free, the next day you may have severe odor episodes - called flares. Our participants will be asked to submit their first sample if they felt they experienced symptoms, or had a day or two different from average. Study participants will be asked to submit responses to our questionnaire about those days.
We will privately follow up with suggestions to improve their wellbeing.

Our new Life-quality Test questionnaire will provide a measure for severity of Metabolic Breath and Body Odor and PATM symptoms.

Anyone who may possibly be interested in participating in this study can get a better idea of what it entails and is welcome to take the first version of this Life Quality Test.

María

María de la Torre
Founder and Executive Director

A Public Charity
maria.delatorre@meboresearch.com
www.meboresearch.org
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Monday, April 23, 2018

The MEBO Wholly Volunteer Staff

OUR VOLUNTEER STAFF

The whole MEBO Volunteer staff is highly thankful to the countless efforts of their Executive Officer, Maria de la Torre, for the establishment and operations of the international MEBO Organization for past 10 Years. You are the pride of whole MEBO community throughout the world.

FOUNDER AND EXECUTIVE DIRECTOR

Maria de la Torre
Founder and Executive Director, MEBO Research
maria.delatorre@meboresearch.org

SCIENTIFIC DIRECTOR AND CONSULTANTS

The MEBO community around the world is most appreciative of our Scientific Director and many MEBO Consultants, who have been steadfastly supportive and dedicated to the MEBO Mission throughout these past 10 years. We are very proud of them.

Dr. Irene Gabashvilli
Principal Investigator and Scientific Director of MEBO US
irene.gabashvili@meboresearch.org
irene@aurametrix.com

Dr. Elizabeth Shephard
Consultant and Principal Investigator of MEBO UK
info@meboresearch.org

Nigel Manning
Principal Scientist ofSheffield Children’s Hospital
info@meboresearch.org

Dr. H****
Consultant of MEBO
info@meboresearch.org

Public Relation Director


Karen James
Director ofPublic Relations UK
karen.james@meboresearch.org

Glenna Gonalez
Director ofPublic Relations US
glenna.gonzalez@meboresearch.org

Managing Director

Mike
MEBO Managing Director
mike@meboresearch.org

User Experience and Technology Director

Jason
User Experience and Technology Director
info@meboresearch.org

Community Outreach and Strategic Director

Mehmet Ali
Community Outreach and Strategic U.K. Director
m.ali@meboresearch.org
muhammadali28121998@gmail.com

Community Outreach Director

Akiya Brownning
U.S. DirectorCommunity Outreach
akiya.browning@meboresearch.org

Mental Health Director

Crissan Rosalia
Mental Health Director of MEBO
c.rosalia@meboresearch.org
takechartge@re-charge.org

Mexican Affairs Director

Maria Cristina Sanchez Lopez
Director of Mexican Affairs of MEBO
maria.cristina@meboresearch.org

Director of Peruvian Affairs

Maria Claudia
Director of Peruvian Affairs of MEBO
info@meboresearch.org

Director of Brazilian Affairs

Thiego
Director of Brazillian Affairs MEBO
info@meboresearch.org

Japanese Study: Elevated petrochemicals in PATM


Japanese TV show, "World Astonishing News"

PATM, which stands for People are Allergic To Me, is a condition in which the sufferer notices that people around him or her tend to experience allergic reactions, which eventually subside after the sufferer steps away from the person.

In Japan the topic of PATM seems to be very prominent. While many medical professionals there consider it to be a delusional mental disorder (Olfactory Reference Syndrome (ORS), Jikoshu-kyōfu) there are also some experts who believe that it really exists, and are carrying out research in an attempt to help PATM sufferers understand the cause of their condition. A study carried out by Drs. Yasuhiro Konishi, M.D., of the Konishi Clinic in Japan, and a researcher, Professor Yoshika Sekine, involved a skin gas test of PATM patients, which showed that the PATM patients had abnormally high amounts of petrochemicals. Even though in most cases, the elevated chemical was toluene, also known as toluol or methylbenzene, there were also other elevated petrochemicals. It is normal to have these chemicals in the human body, but in low amounts. Toluol is also used in paint thinners and known for its irritating effects on the nervous system, eyes and respiratory system.

These finding would suggest that there is the possibility that petrochemicals may very well be the underlying cause of PATM. More research into this condition would be most helpful in order to be able to help PATM sufferers control the levels of these chemicals to enrich their social life and potentially their health. MEBO is poised and ready to research further into these and possibly other metabolites resulting in PATM.

The Japanese TV show, "World Astonishing News" presents a classic case of PATM, allows the researchers the opportunity to be interviewed and to present their findings and analysis on this mysterious disease.

Below is the translated summary of the PATM part starting at time interval 30:10 of the above YouTube video:


Six years previous to starting treatment for what she would subsequently identify as PATM, this ordinary woman in her 40s noticed strange things happening. She was a teacher at a school and also attending night classes to get a new qualification. One day she started feeling very tired but didn’t have a fever, so she resolved to sleep more but still couldn’t get rid of the fatigue, which continued for a year. She noticed meanwhile that her students noticed a weird smell in class that she didn’t notice. Then they had itchy eyes when she was near them but it stopped when she moved away, then on the other side of the class they’d start up there. Students reported an “old house” or “burnt” or “weird” smell and it also happened to the other teachers.

She started to think she might be the cause so she took lots of time to wash her body and used anti-odour products on her clothes and underwear, and carry an anti-odour spray at all times but it didn’t help and she stopped thinking it could be just her imagination. She explained it to her parents but they didn’t notice any smell. But she felt she was causing bother to those around her so she changed jobs but the same things started up – people coughing and noticing a burnt smell.

Six years after she started noticing the symptoms, she found an article online about PATM and thought it applied to her so she found a hospital that does PATM examinations. The doctor did a “skin gases test” – apparently humans, from kids to the elderly, produce over 300 different types of gas including flatulence, and they are collectively referred to as skin gases. When they did the test the doctor said that she produced high levels of toluene, a petrochemical found in things like glue and contact cement, which is toxic and strictly regulated.

The mechanism behind PATM is still not understood but one theory is that skin gases given off by sufferers cause allergy-like reactions in those around them. More research is needed to find if this is the real cause of the condition, but the doctor says that when they examine people who report PATM-like symptoms, in almost 100% of cases they find high levels of petrochemicals. The graph shown at 40:35 shows levels of xylene, 2-ethyl-1-hexanol, ethylbenzene and toluene in non-PATM person/s (green), and two different people who report PATM (red and blue). Those people did indeed have high levels of various chemicals. The chemical found to be high in the woman this report is about, toluene, smells of paint thinner or gasoline, and can sting the eyes, nose and throat. It is found in all human bodies in small amounts but this patient had very high levels. The exact relationship between the smell and the symptoms is not yet fully understood but it is possible that if there were people sensitive to this chemical around such a person, they could potentially show allergy-like symptoms.

The patient has been treated for PATM for the past two years and is taking various supplements to improve her digestive system and her body’s ability to remove toxins. As shown in the video at 43:40, with the patient’s permission, they have someone get up close to her face and fail no notice any kind of smell or sting in their eyes etc.. While she had a great improvement with this treatment, since the exact causes of PATM are not yet known, this isn’t a treatment that all sufferers could benefit from. There is no “wonder drug” for PATM – the patients are treated by trying to “balance their bodies” and some are helped while some aren’t.

María

María de la Torre
Founder and Executive Director

A Public Charity
maria.delatorre@meboresearch.com
www.meboresearch.org
www.mebo.com.br/
MEBO's Blog (English)
El Blog de MEBO (español)
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Professor Yoshika Sekine's Slideshow PATM study

Click on icon & scroll down to see
complete slideshow presentation

Click English translation
The MEBO Research community around the world is most grateful to researcher Professor Yoshika Sekine, for carrying out a much needed study into PATM and for publishing a paper on his findings (in Japanese). In addition, we are most grateful to Professor Sekine and his colleague, Dr. Yasuhiro Konishi, M.D., of the Konishi Clinic in Japan for presenting a classic case of PATM in the Japanese TV show "World Astonishing News", as noted in a post in this blog, "Japanese Study: Elevated petrochemicals in PATM". This research discusses the petrochemicals found in skin gas analysis of sufferers of this syndrome. You have provided our international community with information we can now use in our Raising Awareness Campaign, and for this, we are profoundly grateful!


‘An exploratory study on “people allergic to me” syndrome based on measurement of trace gases released from skin surface and microbial species in nasal cavity of a patient’


Abstract

There exist some people who claim his/her body odor provokes allergy-like reactions of people in their near vicinity, which include sneezing, runny nose, cough, itchy eyes, and red eyes. Such a diathesis, called “people allergic to me (PATM)”, has been gradually recognized in other countries. However, the term “PATM” has been hardly heard in Japan, and there have been no reports focusing on PATM in academic journals so far. After receiving a request for advice from a male subject, we conducted a medical interview, measurement of trace gases released from human skin surface, measurement of volatile chemicals from the subject’s underwear, and microbiological test of the nasal cavity of the patient. The results showed that greater amounts of chemicals, such as toluene and xylene, were detected in skin-gas samples from the subject than in those from a control subject. Moreover, some chemicals, such as hexane, propionaldehyde, and toluene, which showed relatively high levels of emission from the subject’s skin, were also detected in the underwear of the subject. The microbial species that was isolated from the nasal cavity of the subject with the highest abundance was Staphylococcus epidermidis (Bacilli; Bacillales), which is known as a resident skin flora. In addition, Arthrobacter phenanthrenivorans (Actinobacteria; Micrococcales), which releases a ditch-like smell, was cultured on isolation medium, and its presence might have a relationship with the PATM condition. Furthermore, Rhodotorula mucilaginosa (Basidiomycota; Sporidiales), which is a fungus that is known to cause red water scale in bathrooms/washrooms, was isolated from the nasal cavity of the subject. To the best of our knowledge, the isolation of this latter species from the human nasal cavity has not previously been reported. Taken together, there is a possibility that PATM is not a product of patients’ imagination but represents a genuine disease that has yet-to-be-investigated.


Citation:
KAWAKAMI, Yuji & SEKINE, Yoshika & KIMURA, Keita & TODAKA, Michihito & ODA, Hisayuki. (2018). An exploratory study on "people allergic to me" syndrome based on measurement of trace gases released from skin surface and microbial species in nasal cavity of a patient. Indoor Environment. 21. 19-30. 10.7879/siej.21.19.


Online link to the full publication: https://www.researchgate.net/publication/324134401_An_exploratory_study_on_people_allergic_to_me_syndrome_based_on_measurement_of_trace_gases_released_from_skin_surface_and_microbial_species_in_nasal_cavity_of_a_patient




María

María de la Torre
Founder and Executive Director

A Public Charity
maria.delatorre@meboresearch.com
www.meboresearch.org
MEBO's Blog (English)
El Blog de MEBO (español)
MEBO Brasil - Blog (Portuguese)



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Raising Awareness about PATM

It is MEBO’s aim to allow its members from around the world to have a voice and the opportunity to tell their story to the world. For this reason, the MEBO Raising Awareness Campaign was created. This video is made by a young university student in the Middle East, who wants the opportunity to comment on the study carried out by Professor Yoshika Sekine and his team of researchers (2018). The graphs shown in this video taken from Professor Sekine’s Slideshow presentation for the MEBO Conference clearly show the presence of chemicals and microbes found on PATM subjects.

In this video, Muhammad also addresses Olfactory Reference Syndrome (ORS), which many in the medical community resort to, for lack of research to form a more targeted diagnosis. It is for this very reason that the American Psychiatric Association (APA) listed ORS in the Appendix for Further Research classification. It is now classified as “an Obsessive Compulsive Spectrum Disorder with a strong anxiety component. As such, it belongs in the new Anxiety and Obsessive-Compulsive Spectrum Disorders category,” says Dr. Jennifer L. Greenberg, Psy.D., with the Massachusetts General Hospital and Harvard Medical School., who studied our MEBO community in 2010. This classification now calls for mental health therapy for body odor and PATM sufferers to be focused on treating the anxiety and obsessive-compulsive disorder that comes with having these conditions, as opposed to being administered medication for delusional symptoms, in order to help sufferers become functional members of society.


While many delusional patients are treated with antipsychotics, Greenberg said, "What we are starting to think more about is that the disorder presents like disorders that are closer to obsessive compulsive disorder.

This MEBO member who suffers from PATM Syndrome, represents a large sector of the MEBO population who have observed how those around them, and in some cases their own children, experience allergic reactions when they are near the PATM sufferer. “It’s like ‘the cat’ entered the room, and my kids start to sneeze, get teary eyed, when they get near me, and then their symptoms stop when I leave! I am their father, and I want to be able to be with them without inflicting these symptoms on my own kids!” says a PATM sufferer.

Thank you Muhammad for telling your story and representing the whole PATM community around the world.


María

María de la Torre
Founder and Executive Director

A Public Charity
maria.delatorre@meboresearch.com
www.meboresearch.org
www.mebo.com.br/
MEBO's Blog (English)
El Blog de MEBO (español)
MEBO Brasil - Blog (Portuguese)



SUPPORT THE MEBO MISSION: Click Amazon button at right sidebar of this blog when shopping online for the holidays
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